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Spacing Pfizer COVID shots boosts antibody levels in long-term study

LONDON (Reuters) -A longer gap between doses of Pfizer’s COVID-19 vaccine leads to higher overall antibody levels than a shorter gap, a British study found on Friday, but antibody levels are not sustained for long after the first dose. The study might help inform vaccination strategies against the Delta variant, which reduces the effectiveness of a first dose of the vaccine even though two doses are still protective, and one author said that Britain’s eight-week gap was a “sweet spot” against Delta. “For the longer dosing interval … neutralising antibody levels against the Delta variant were poorly induced after a single dose, and not maintained during the interval before the second dose,” the authors of the study, which is being led by the University of Oxford, said.

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