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Delta variant will lead to increase in breakthrough Covid infections among vaccinated, Moderna says

A healthcare worker treats a patient inside a negative pressure room in the Covid-19 intensive care unit (ICU) at Freeman Hospital West in Joplin, Missouri, on Tuesday, Aug. 3, 2021.

Angus Mordant | Bloomberg | Getty Images

The highly contagious delta variant will lead to an increase in breakthrough infections among the fully vaccinated as people begin moving indoors after the summer, Moderna said Thursday.

While Moderna’s two-dose vaccine remains “durable” six months after the second shot, immunity against the coronavirus will continue to wane and eventually impact vaccine efficacy, the company said in slides that accompanied its second-quarter earnings report.

The company said its vaccine is 93% effective six months after the second dose. By comparison, Pfizer and BioNTech said their vaccine efficacy declined to around 84% after six months.

“Given this intersection, we believe dose 3 booster will likely be necessary prior to the winter season,” Moderna wrote.

The warning by Moderna comes as the delta variant continues to spread in more than 100 countries, including the United States. Delta, the dominant form of the disease in the U.S., is more transmissible than the common cold, the 1918 Spanish flu, smallpox, Ebola, MERS and SARS, according to the Centers for Disease Control and Prevention.

For some Americans, concerns about vaccine efficacy have intensified with the rise of the variant, which spreads more easily and may cause more severe disease than the original coronavirus. Some people have gone as far as seeking out a supplemental dose, which is not yet recommended by the CDC. This week, San Francisco health officials said they are allowing patients who received Johnson & Johnson’s vaccine to get a second shot produced by either Pfizer-BioNTech or Moderna.

Drugmakers have said for months they expect people will eventually need booster shots and perhaps extra doses annually, just like for the seasonal flu.

The CDC and the World Health Organization say booster doses are not needed at this time, citing lack of data. In fact, the WHO on Wednesday called on wealthy nations to stop the distribution of Covid booster shots to give the world a chance to meet the director-general’s goal of vaccinating 10% of the population of every country by the end of September.

“We need an urgent reversal from the majority of vaccines going to high-income countries, to the majority going to low income countries,” WHO Director General Tedros Adhanom Ghebreyesus said at a press briefing.

This is a developing story. Please check back for updates.

CNBC Health & Science

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